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Revealed: The saliva test that detects early signs of stroke

From the Daily Mail (U.K.):

A simple saliva test could help doctors identify patients most at risk of a life-threatening stroke.

New research shows that high levels of the hormone cortisol in saliva are directly linked to the build-up of fatty deposits in arteries carrying blood to the brain.

When these deposits - called plaques - break loose, they can cause a blockage that starves the brain of blood and oxygen.

Research published in the Journal of Clinical Endocrinology and Metabolism suggests many strokes could be prevented if doctors routinely tested patients' saliva.

Strokes are the third most common cause of death in England and Wales, after heart disease and cancer. They occur when a clot cuts off the blood supply to the brain.

Clots are often caused by fatty deposits that get dislodged and travel towards the brain. Once they get into smaller blood vessels in the skull, they cause a blockage.

In the latest study, experts at the Erasmus Medical Centre in Rotterdam, Holland, and the Technical University of Dresden in Germany tested volunteers to see if cortisol levels in their saliva pointed to diseased arteries.

Each volunteer provided four saliva samples throughout the course of one day and underwent ultrasound tests to check for plaque deposits in their carotid arteries (in the neck).

The results showed those with the highest cortisol levels also had the largest build-up of plaques.
Posted: 10/29/2008 9:46:00 AM

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